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To date, leading theories about the mechanisms include changes in molecular signaling chemicals released by bacteria in contact with local tissue or distant organs (Schroeder and Backhed, 2016; Meijnikman et al., 2017) (Fig. 1).
Proposed killing mechanisms include: changes in salinity; poisoning by chemicals such as hydrogen sulfide or methane; changes in the availability of oxygen; and changing consistency of the sea floor.
Long term mechanisms include changes in Th synthesis [ 34].
19 20 Other potential mechanisms include changes in baroreceptor sensitivity, natriuresis and reduced systemic vascular resistance.
Potential mechanisms include changes in the intracellular K+ and Ca2+ concentrations.
These mechanisms include changes in cell-cell and cell-matrix adhesion molecules, extracellular matrix degradation enzymes, cytoskeleton regulation factors and cell-cell communication through cytokines, for example [ 1].
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Obesity and obesity-related comorbidities may lead to asthma via a number of mechanisms including changes in lung mechanics, the nitric oxide metabolism, and by causing inflammation.
Although gap junction channels are relatively nonselective in their permeability to ions and small molecules, cardiac myocytes actively adjust their level of coupling by multiple mechanisms including changes in connexin expression, regulation of connexin trafficking and turnover, and modulation of channel properties.
The Affordable Care Act includes a projected half a trillion dollars in savings through a variety of mechanisms, including changes in reimbursement rates to hospitals and by reducing over-payments to private Medicare advantage plans.
The reduced responsiveness of the MCs from pregnant rats to Ang II may be caused by many potential mechanisms, including changes in the expression of the receptors for Ang II and for other vasoactive substances.
These effects of C479T replacement on channel gating may originate from a number of mechanisms including changes in pore structure and thereby ion binding, possibly leading to altered pore-gating in selectivity filter as reported previously in K+ channels [32], [50], [51].
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