Your English writing platform
Discover LudwigSuggestions(2)
Exact(3)
So far, proposed mechanisms include altered metabolism of glucose via the polyol pathway, advanced glycation end products, increased protein kinase C (PKC) activity, altered neurotropism, perturbation of lipid metabolism, ischemia and reactive oxygen species [4], [6], [9], [10].
Potential mechanisms include altered AA metabolism in the liver, kidneys, muscle or adipose tissue [ 29– 31].
Alternative ligand-dependent mechanisms include altered steroid biosynthesis in the tumor microenvironment, increased 'backdoor' synthesis of DHT, and circumvention of testosterone as the precursor [ 31, 54].
Similar(57)
DPRs elicit toxicity through a number of mechanisms, including altered ribosomal biogenesis, impaired nucleocytoplasmic transport, shifts in RNA metabolism, protein sequestration, and impaired protein quality control pathways13, 16,17,18,19,20,21.
Oral contraceptives and hormonal replacement therapy increase the risk through a variety of mechanisms, including altered blood coagulation protein levels and reduced fibrinolysis.
Animal studies suggest plausible causal mechanisms, including altered brain neurotrophic factors and decreased inflammation.
Analysis of various potential mechanisms, including altered drug transport, detoxification mechanisms and DNA repair [32], did not unequivocally identify the critical cause of the extraordinary sensitivity of TGCT cells.
Since circulating 17β-estradiol levels were not measured in this study, we can only speculate that possibly the observed increase in FSHR levels in UNL offspring may be a result of other hormonal mechanisms, including altered 17β-estradiol levels.
These changes in gene expression could occur via several mechanisms including altered gene looping or genome architecture [ 6– 10].
ROS may directly alter vascular function or cause changes in vascular tone by several mechanisms including altered NO bioavailability or signaling [ 35].
We have already shown that modulation of ERs is both complex and indirect, the latter mechanisms including altered expression of homeostatic protein hsp-27 (O'Neill et al, 2003).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com