Sentence examples for mechanisms include alterations from inspiring English sources
Potential mechanisms include alterations to the pain-modulating dopaminergic system and carbergoline, an ergot derivative, also possesses significant affinity for certain subtypes of serotonergic and adrenergic receptors.
Other possible resistance mechanisms include alterations in the proteolytic processing of the Bt-protoxin and rapid regeneration of the damaged midgut epithelium [27].
Epigenetic mechanisms include alterations in DNA methylation, histone modification, and microRNA [ 13, 14].
The exact pathogenesis of IBS is generally unknown but postulated mechanisms include alterations in gut motility, visceral hypersensitivity, bacterial flora, together with psychological association [ 5- 7].
Alternative mechanisms include alterations in drug uptake and metabolism, enhanced DNA repair proficiency, or activation of survival by other signaling pathways such as PI3-kinase/Akt.
Postulated mechanisms include alteration in blood viscosity, enhanced vascular reactivity and improved vasoconstriction following correction of anaemia [ 54].
Other immunologic mechanisms include alteration of the cytokine profile and activation of macrophages to present antigen to B lymphocytes and increase immunoglobulin production [ 20].
These mechanisms include alteration of intracellular Ca2+ signaling via ryanodine receptor activated Ca2+ stores and reactive oxygen species, as discussed by Powers et al. (2006), though these hypotheses may not be extrapolatable to humans.
Such associations are plausible through several biological mechanisms, including alterations to vasomotor tone [33], [34], thrombogenic effects [35] and the induction of systemic inflammation [36].
In undifferentiated, highly proliferative malignant cells, butyrate inhibits proliferation and induces differentiation through a variety of mechanisms including alterations in DNA methylation, selective inhibition of histone phosphorylation and histone deacetylation (HDAC), and modulation of intracellular kinase signaling [5] [7].
In Neisseriae, phase variation can occur through several mechanisms including alterations in the number of short sequence repeats in the coding region of genes or through variation in poly-nucleotide stretches in promoter regions [56], [57].
