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Recent advances present an opportunity to apply the tools of forward genetic analysis to identify mutations that affect these mechanisms in zebrafish.
Our data indicating that the lack of shortening of telomeres with age in the zebrafish are of importance to those using the zebrafish as a model of aging, especially for those studies relating aging mechanisms in zebrafish to those in humans.
The approach was applied to investigate 1α, 25(OH)2D3 - altered mechanisms in zebrafish embryo development.
The proposed method was applied to investigate 1α, 25(OH 2D3-altered mechanisms in zebrafish embryOH 2D3-altered
Herein, the first studies establishing the zebrafish as a model for human influenza infection are presented, and it is shown that IAV infection proceeds and can be resolved through similar mechanisms in zebrafish and humans.
The expression pattern of miRNAs associated to each tissue and gender can serve as a useful resource for further research and for understanding the miRNA-mRNA regulatory mechanisms in zebrafish.
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Moreover, it has also been demonstrated that gata1 expression undergoes a positive autoregulatory mechanism in zebrafish [24].
Ultimately, understanding disease mechanism in zebrafish disease models can lead to new treatments.
The data confirm interaction of those compounds with the rhodamine B efflux mechanism in zebrafish embryos that, as we show here, is Abcb4.
Taken together, our analyses revealed the piRNA to miRNA transition as a conserved mechanism in zebrafish, although two different types of sRNAs exhibit distinct expression dynamics in abundance and diversity, respectively.
At the same time, immune responses, apoptosis, ion transport, and protein secretion were found to be crucial molecular defensive mechanisms occurring in zebrafish in response to the pathogen.
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