Sentence examples for mechanisms in asthma from inspiring English sources
Immunological mechanisms in asthma concerning the adaptive immune system have been reduced to the imbalance between Th1 and Th2 CD4+ T cells for many years.
However, other factors are important within the disease per se, e.g. non-IgE mechanisms in asthma.
It has been postulated that isocapnic hyperpnea of dry air (IHDA) and hypertonic aerosols act via similar mechanisms in asthma to cause bronchoconstriction.
By contrast with anaemia, arthritis and cancer, evidence about the underlying mechanisms in asthma is much less well-established, with most existing evidence coming from patients with long-standing and clinically severe asthma; further research in broader populations is needed.
An improved understanding of the molecular mechanisms in asthma through exploring the role of miRNAs is expected to create promising potentials to reveal new approaches for primary prevention and identification of new therapeutic targets in childhood asthma.
These include genes involved in diverse roles including inflammatory cell function and activation (IL13, IL6R, DENND1B, LRRC32, IL2RB, IL1RL1), airway smooth muscle contraction (PDE4D), and cell apoptosis and differentiation (GSDMB) again providing a unique insight into potentially altered mechanisms in asthma.
This raises the question if airway wall fibrosis is irrelevant for lung function or even if fibrosis provides a protective mechanism in asthma contributing to airway patency rather than to airflow limitation.
Luukkainen and colleagues explore the possible mechanisms present in asthma and CRS with nasal polyps among patients residing in urban environments, while Jeong et al. suggest the utility of nasal nitric oxide levels in screening for CRS with polyposis.
The aim of this qualitative study was to explore those mechanisms in paediatric asthma care that lead to deficiencies in the care process for ethnic minority patients.
To develop effective training, we explored the mechanisms in paediatric asthma care for ethnic minority patients that lead to deficiencies in the care process.
(A12)" In this study we showed that mechanisms in paediatric asthma care that lead to deficiencies in the care process for ethnic minority children were mainly related to non-adherence.
