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However, further evolution of regionally tailored renewable energy policy will be required as auction mechanisms gain traction and renewable energy becomes increasingly prominent.
Furthermore, regulatory mechanisms gain another dimension of complexity by various microRNAs that have been implicated in regulation of replicative senescence [ 27, 54- 56].
In addition, research by the EPA-funded Southern California Particle Center at the University of California, Los Angeles, published in the April 2003 issue of EHP, demonstrated that ultrafine particles from incomplete combustion of engine fuels and lubricating oils can bypass the body's defense mechanisms, gain entry to cells and tissues, and alter or disrupt normal cellular function.
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Associations with lean mass could be confounded by fat mass; because of adaptive mechanisms, gains or losses in fat typically lead to respective gains or losses in lean mass (20, 21).
Greater understanding of the underlying pathological mechanisms, gained from research using transgenic animals and new stem cell-based technologies, have revealed possible novel therapeutic strategies targeting the underlying pathologies, that is, both Aβ and tau pathology.
The first roadblock (T1) was described by the roundtable as "the transfer of new understandings of disease mechanisms gained in laboratory into the development of new methods for diagnosis, therapy, prevention and their first testing in humans".
When a joint clearance is introduced, the mechanism gains two uncontrollable degrees of freedom.
This mechanism gains support from work on carbon nanopores, through which water moves with incredible speed [27].
It is also possible that they do not use a pure catch-and-release mechanism, gaining power by combining elastic release with real-time muscle contraction.
Regardless of the underlying mechanism, gain-of-function defects in Nav1.5 disrupt the delicate balance between depolarization and repolarization during the action potential plateau phase, thus delaying repolarization and increasing the risk of lethal ventricular arrhythmias.
It concludes by stating that understanding the mechanisms underlying gain modulation is important because gain modulation is a prominent feature of neural activity recorded in behaving animals.
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