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Thirdly, exon/intron structure analysis was performed to gain insight into the possible mechanisms for structural evolution of the OPR gene family, because the exon/intron structural divergence within gene families is also a mechanism for the evolution of multiple gene families.
We quantitatively analysed the microscopic mechanisms for structural mismatch compensation and the mode of the film growth.
It is demonstrated that different mechanisms for structural changes can be identified with this technique: droplet deformation, droplet retraction, fibril break-up and coalescence.
Since the key feature of AS, much unlike rheumatoid arthritis [ 36], is new bone formation rather than osteodestruction, there is reason to consider different mechanisms for structural change which appear on radiographs in these diseases.
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We here hypothesize that for more fragile protein complexes that span two membranes, tertiary structure elasticity may constitute a general mechanism for structural protection.
An increase of hydrogen bonds corresponds to a more compact and rigid protein conformation, which is probably favorable for stabilizing the protein against alkali-denaturation and suggested to be an important mechanism for structural adaptation of a variety of proteins to alkaline environments[22], [28].
Membrane dysfunction may act as the common mechanism for structural changes [ 5, 6, 8, 9] in the course of disease.
Although the underlying mechanism for structural changes is not clear, recent echocardiographic data suggest that structural remodelling is often present in the atrium of elite athletes without AF.
Sequence alignment of XcOGT with hOGT provides a mechanism for structural alignment of the TPRs with conservation of the canonical TPR sequence motif.
Moreover, in conjunction with other modeling techniques, MD can be employed to provide structural models for missing states in the transport cycle and to provide a possible mechanism for structural transitions between major states.
The mechanisms responsible for structural joint protection by MTX are unclear and probably multifactorial.
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