In a way, nudges have been so appealing to policy makers and corporate players alike because they provide a perfect mechanism for directing behavior while respecting individual's autonomy: they left room for real individual choice.
The ubiquitination proteolysis pathway is the primary mechanism for directing proteins to the proteasomal degradation machinery, eliminating unwanted proteins and preserving protein levels in the cell.
Combinatorial cis-regulatory networks encoded in animal genomes represent the foundational gene expression mechanism for directing cell-fate commitment and maintenance of cell identity by transcription factors (TFs).
In CTLs, a novel mechanism for directing secretion precisely via centrosomal docking at the plasma membrane has been described in which polarisation of the centrosome to contact the plasma membrane close to the secretory cleft reorganises microtubules to lie underneath the plasma membrane at this point, and directs secretory traffic to a single focused spot within the immunological synapse.
It is clear now that a variety of mechanisms exist for directing mutations to specific targets that are relevant for adaptation under the given conditions.
Functional investigations by blasting the metagenomic data against public databases may reveal the genetic determinants of microbial interactions, and illuminate the mechanisms responsible for directing the changes in microbial diversity in response to fasting challenges.
The City of Chicago has a mechanism designed for directing funds to blighted properties.
Here, the authors speculate that the RNA polymerase II preinitiation complex exploits the relative instability of the polyrU.dT RNA DNA hybrid in abortive transcription, a mechanism key for directing a programme of coordinated temporal gene expression.
Given the often-times high Km's of glycoslytransferases, the presence of oligomeric assemblies of enzymes in the secretory pathway would be a reasonable proposed mechanism for directed complex glycosylation.
Determining experimentally which of these processes are critical for colonization has been difficult, largely because mechanisms responsible for directed migration, proliferation, and neurite growth share many molecules and pathways, making any experimental separation difficult.
