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We further investigated whether increased transport induced by PDE5 inhibitors was associated with any of these major mechanisms (Figures 3, 4).
Information Theoretic Similarity (ITS) (only applicable for GO-BP mechanisms; Figures 3 and 4 ).
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Aloe-emodin, however, could repair dGMP radical via SEPT and/or HAT mechanisms (Figure 4).
The observations from Figure 6 are summarised below and there are three most commonly proposed mechanisms: Figure 6 Probability function of proposed mechanisms to explain anomalous heat transfer (conduction/convection/mixed mode heat transfer studies).
The observations from Figure 7 are summarised below and there are two most commonly proposed mechanisms: Figure 7 Probability function of proposed mechanisms to explain anomalous heat transfer (pool boiling heat transfer and CHF heat transfer studies).
In contrast, the disease prevalence peaks in moderately large households for the genetic mechanisms (Figure 3B).
Of those with RCPF, 24 (21.3%) also had other mechanisms (figure 2).
However, upon ligand stimulation IGF1R was internalized by clathrin-dependent mechanisms (figure 1B) and by CAV1-dependent mechanisms, although to a lesser extent (figure 1A).
Interestingly, plc1Δ and isc1Δ, two strains deficient in Plc-like activity, led to a small, but significant increase in PEA hydrolysis, suggesting compensatory mechanisms (Figure S1).
As anticipated from the previous studies, within these pathways we find Ubx targets at multiple levels from ligands to receptors and effector mechanisms (Figure 2).
Firstly, while the pMV-absorption proceeds via complex cellular and molecular mechanisms (Figure 3), the assay itself is simple and expeditious and thus can be easily implemented as a high throughput assay (Figure 4A).
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