Although this approach extends biocompatibility to the materials, further studies suggest that biorecognition mechanisms exclude them from biodistribution and either prevent them from drug delivery or their efficiency is minimized.
Being very conscious of this aspect, we implemented numerous mechanisms to avoid wrong results; during both GPKB construction and transitive relationship processing, these mechanisms exclude data items that must not be taken into account, or of low quality.
Lee et al. 4 and Orthwein et al. 3 converged on phosphorylation of these residues as the mechanism excluding 53BP1 from localizing to mitotic IRIF (Fig. 1).
As an example, the adaptive frequency hopping mechanism excludes channels with bad communication quality from the channel list[30].
Spatial condition: 3-D mobility of the end-effector is required (i.e., planar 3-DoF mechanism excluded).
However, the presence of some large particles, which may grow based on the diffusion mechanism, exclude evaporation and the homogenous nucleation mechanism.
Such a mechanism excludes channeling of the methylated intermediates from one active site to another, and is in agreement with a random enzyme reaction mechanism [ 28].
We obtained an acceptable fit for each of the six mechanisms, thereby excluding none of the possible underlying mechanisms for heterogeneity of susceptibility to leprosy.
For the case of double-node resistance mechanisms, and excluding those that target the apoptosis and proliferation pathways, we identify several new resistance mechanisms involving the AKT, MAPK, mTORC1, or ER pathways (Table 2).
But the causes are fundamentally about the political and cultural mechanisms of excluding people from economic and social justice.
