Protein tyrosine phosphorylation and ubiquitination serve as key regulatory mechanisms downstream of the TCR.
Humans with naturally occurring amblyopia show deficits thought to involve mechanisms downstream of V1.
These studies have helped understand mechanisms downstream to the α-synuclein oligodendroglial accumulation relevant to human MSA.
In this review we focus on recent findings about the signaling mechanisms downstream of mTORC1 that regulate lipid metabolism in the liver.
There is growing evidence for divergent mechanisms downstream of receptor activation by BMPs.
DHPs targeting the mechanisms downstream of ET-1 signaling may offer more appropriate therapeutic options in that context.
In the experiments presented here, we examined the mechanisms downstream of TLR2 in mediating this inhibition, by using the specific TLR2/1 agonist Pam3CSK4.
The mechanisms downstream of SERT blockade that are responsible for the therapeutic effects of SSRIs remain unknown, despite recent advances [6].
Although many studies have investigated the activation of Ub and its transfer to substrates [10], the biochemical mechanisms downstream of ubiquitination are not completely understood.
Single cell analysis and culturing under differentiation condition of the TAG1 induced cells should be more informative on lineage commitment mechanisms downstream Smad2/3 signalling.
The observations that filopodia and cortical actin networks formed in SYT-ablated cells indicate that many of the mechanisms downstream of integrin ligation - particularly events mediated by the small GTPases Rac and cdc42 [29] - are not dependent on SYT.
