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Aberrant splicing in cancer is typically associated with changes in the abundance/activity of the regulatory splicing factors by multiple mechanisms (copy number, transcription and phosphorylation).
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The mechanisms whereby copy number variants confer this effect are not yet known.
When you rip the DVD, you strip off those mechanisms but copy the rest of the video unadulterated.
The precise mechanism whereby copy number is associated with IgE levels is unclear.
We can infer that, in L228-3, a different molecular mechanism to copy number variation (CNV) would enhance ZmMATE1 expression under Al stress, conferring an important advantage to acid soils adaptation.
This research designs an international collaboration mechanism by copying successful features from existing international collaboration mechanisms.
Underlying mechanisms by which copy number deletions at these regions and others may contribute to autoimmunity remains to be determined.
We also explored the use of QTL to map mechanisms that regulate copy number in the progeny of the genetic cross.
Class I TEs (or retrotransposons) transpose via a "copy-paste mechanism" by copying themselves into an RNA-intermediate before inserting at a new site, while class II TEs (or DNA transposons) leave the donor site to reintegrate at another site via a "cut-paste mechanism", although the original copy can also be retained [ 13].
By contrast to the single mechanism for copying genetic information by semi-conservative replication, recent studies suggest that copying of the epigenetic information is a lot more complicated and varied.
Our analysis provides insight into the underlying mechanism of cristae copy number and distribution control.
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