Whereas mechanisms controlling the differentiation of Th1 cells, Th17 cells, and regulatory T-cell subsets are well described, the issue of Th2 differentiation is still being debated.
The HESCs derived from these leftover embryos offer investigators a powerful tool for understanding the mechanisms controlling cell differentiation.
However, the molecular mechanisms controlling OL differentiation are largely unknown.
The mechanisms controlling the differentiation of mesenchymal stromal cells (MSCs) towards osteoblasts, i.e osteoblastogenesis, are less understood.
However, the physiological mechanisms controlling this differentiation are largely unknown.
The mechanisms controlling the differentiation process of ESCs are poorly understood.
The aim of this review is to give an appreciation of both the beneficial and detrimental roles of the myofibroblast in the remodelling heart, to describe some of the major regulatory mechanisms controlling myofibroblast differentiation including recent advances in the microRNA field, and to consider how this cell type could be exploited therapeutically.
To accurately describe the regulatory mechanisms controlling HSC differentiation, the important aspects that any mathematical model of the GATA-1-PU.1 network must include are an indeterminate state for the progenitor cells and two stable attractors of the dynamical system for the differentiated lineages.
To explore the molecular mechanisms controlling ES cell differentiation into cardiomyocytes, we used an αMHC-based reporter system to profile the temporal gene expression of cardiac markers during ES cell differentiation.
Therefore, sole species have become a suitable model to study larval ontogeny, skin pigmentation, hormonal and epigenetic mechanisms controlling development, sex differentiation, nutritional requirements, asymmetrical development as well as comparative genomics in flatfish [ 7– 10].
