Our data suggest a possible mechanism by which PKCε can access cytoprotective substrates located within the mitochondria to confer cardioprotection.
Moreover, since SIRT1 is an NAD-dependent de-acetylase with multiple cellular targets, the discovery that HPV E7 up-regulates SIRT1 protein levels identifies a new mechanism by which HPV can access diverse SIRT1-dependent regulatory systems in human cervical keratinocytes.
Imaging is becoming an important key technology in this process, with its ability to deliver non-invasive and quantitative cellular and molecular information that can access the mechanisms of drug action.
Finally, the journal hired statisticians to help with review, and it provided a mechanism by which the public can access raw data used to generate published tables and figures.
VPNs use encryption and other security mechanisms to ensure that only authorized users can access the network.
This constrains the amount of health care we can access and offers no mechanism for responding to patients' preferences.
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