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Exact(7)
Although the mechanism is not well understood, TBI due to blunt trauma is widely thought to be caused by any combination of three possible mechanisms: an increase in pressure within the airways, shearing, and pulling apart.
Together, our results indicate that the increased BimEL expression induced by AZD6244 treatment could be caused by two mechanisms: an increase of Bim gene transcription and an inhibition of Bim protein degradation.
The anti-apoptotic effect was associated with two different mechanisms: an increase of Bcl-xL (anti-apoptotic marker) levels and a decrease of Bid (pro-apoptotic marker) levels.
Treatment was designed to operate by one of two mechanisms: an increase in cured fraction, or an increase in median tumour-related survival time among uncured patients.
Commonly used drugs such as RAAS blockers or beta-blockers may affect not only the targeted system, but may also cause, via feedback loops or compensatory mechanisms, an increase in other factors involved in the cardiorenal interaction.
Other than HER2 related mechanisms, an increase in p53 mutations [ 69, 70], the accumulation of genomic imbalances [ 70, 71], and the response to, and secretion of, stem cell growth factors (epidermal growth factor, fibroblast growth factor) [ 42, 72, 73] could be involved in the 'awakening' of dormant DTCs.
Similar(53)
Possibly due to a similar mechanism, an increase in VEGF-A level in cell culture media by the addition of soluble heparin has been reported previously [28].
Despite the uncertainty regarding the underlying mechanism, an increase in antagonist muscle tension would clearly affect wrist joint dynamics.
As a mechanism, an increase in plasminogen activator inhibitor 1 (PAI-1), which is produced by endothelium and liver, has been demonstrated [ 18].
Consistent with this mechanism, an increase in ROS upon using inhibitors of the mitochondrial electron-transport chain was shown to synergize with the MDR-selective toxicity of verapamil.
These types of enhancers could be regulated by a negative feedback mechanism: an increase in transcription leads to a decrease in enhancer activity, thereby preventing excessive activation of the target gene.
More suggestions(14)
system an increase
mechanisms an investigation
mechanisms an approximation
mechanisms an aspect
mechanisms an imbalance
mechanisms an observation
mechanisms an architecture
mechanisms an individual
mechanisms an area
mechanisms an isotropic
mechanisms an example
mechanisms an approach
mechanisms an enzyme
mechanisms an animal
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