Sentence examples for mechanisms activation of from inspiring English sources

Both components lead to diabetes complications through two major mechanisms: activation of oxidative stress and increased activity of the innate immune system (7, 8).

Thus PKD2 can regulate myogenic differentiation by affecting two transcriptional mechanisms, activation of Mef2D and inhibition of Pax3 transcriptional activity.

Among the EGFR downstream signalling mechanisms, activation of the MAPK cascade has special relevance in the regulation of inflammatory events.

Telomere length is maintained by two known mechanisms, activation of telomerase or alternative lengthening of telomeres (ALT).

This issue will give insight into cellular and molecular mechanisms, activation of signaling pathways, how activation of these pathways causes muscle dysfunction, and subsequent disease symptoms.

These effects have been attributed to changes of transcription rates, interference with DNA repair mechanisms, activation of cellular differentiation, and histone modification (Gadhia et al. 2012).

However, unlike the case for the mono-zinc mechanism, activation of Thr285 by proton transfer to Asp465 resulted in a significant structural change in the active site that involves dissociation of this residue from the Zn1 metal ion.

We considered one mechanism: activation of the hypothalamic pituitary adrenal (HPA) axis [ 41 48].

Perhaps by this mechanism, activation of NF- κB can protect leukemic cells from apoptotic killing (Jeremias et al, 1998).

These studies help to understand the mechanism activation of catB which might help in designing new catB inhibitors.

We tested the hypothesis that these responses are linked by a common mechanism-activation of the arterial baroreflex.