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In addition, a 46 mV per decade Tafel slope was obtained, evidencing that the ORR mechanism would involve a chemical step following the first electron transfer, or, the rate determining step would be the transfer of a second electron.
Majority Leader Harry Reid said the mechanism would involve a new law binding Congress to reduce the deficit.
Like in seasonal influenza, its mechanism would involve apoptosis via the fas-fasL pathway [37].
Part of this mechanism would involve an interaction in which PACS-1 connects Nef and AP-1 [21].
The gating mechanism would involve a dynamic selection of behaviorally relevant stimuli and suppression of competing stimuli, as we have been measuring in this study.
For example, one plausible mechanism would involve severe epithelial injury leading to exposed fibrous lamina propria, allowing fibroblast precursors to migrate from the ulcerated airway wall into the lumen.
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Many of these mechanisms would involve decrepitation of the fluid inclusions, as is widely observed [20].
However, several theories have been proposed and can be divided into two main groups namely, peripheral theories with mechanisms involving a dysfunction in cervical spinal nerves (predominantly C3 root) and central theories in which the underlying mechanisms would involve a dysregulation of brainstem trigemino-autonomic circuits.
Hemi-fusion mechanisms would involve SNAREs.
However, to explain the data by such mechanisms would involve larger flows than are currently known to occur (Charles Nicholson and Tony Gardner-Medwin, personal communications) and would further require that these flows vary with behavioural state.
While these mechanisms would involve intact healthy cells, a critical unaddressed question remains the role that neuronal injury/death may play in facilitating α-syn access into the extracellular space.
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