Sentence examples for mechanism to attenuate from inspiring English sources

In this study, we investigated the regulation of p38 MAPK in cardiac remodeling elicited by endogenous adrenergic mechanisms.Transgenic male and female mice with fourfold phospholamban (PLB) overexpression exhibited enhanced circulating norepinephrine (NE), as a physiological compensatory mechanism to attenuate PLB's inhibitory effects.

As an intracellular defense mechanism to attenuate ER stress and maintain organism homeostasis, the UPR is involved in the pathogenesis] of numerous human diseases, including ovarian diseases.

Differences in ADL digestion coefficients between sheep and goats support Howe's suggestion that goats may have a mechanism to attenuate the undesirable effects of lignin (Howe et al. 1988).

Long-term, but not acute, loss of Cdk5 led to decreased p25 levels, suggesting that Cdk5/p25 may be activated as a homeostatic mechanism to attenuate epileptiform activity.

Accordingly it is tempting to speculate that differentially up-regulation of ADORA1 is a negative feedback mechanism to attenuate the higher FFA release observed in EAT [5].

Mdm2 may utilise more than one mechanism to attenuate hTR promoter activity (Fig. 5).

In this study, we evaluate the performances of several major mechanisms to attenuate the fluctuation in a single-gene expression; noise attenuation through the control of the ratio of the transcription rate to the translation one, the interaction between synthesized proteins and background molecules, and an autoregulatory negative feedback.

Given the growth-suppressive consequences of activating the DDR, tumour viruses have also evolved mechanisms to attenuate these pathways.

One of the mechanisms to attenuate insulin resistance is preoperative administration of carbohydrate-rich liquid drinks (CRLDs) [ 6].

Though there may be multiple mechanisms to attenuate MCC expression in HCC, the present study demonstrates that miR-494 is one such way to directly target MCC.

The above experimental studies indicate that the positive association of OPG with vascular calcification in humans may not be necessarily causative, and it remains unclear whether increased OPG levels promote arteriosclerosis, or merely represent a compensatory mechanism aiming to attenuate further vascular injury [ 16, 44].