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Notwithstanding the mechanism, these differences afforded a key test for the specificity of Ivermectin in vivo.
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Although the mechanism for these differences remains unknown, hypoxia-induced metabolic depression likely plays a role.
One potential mechanism for these differences is the differential expression of PTP-PEST, a tyrosine phosphatase known to dephosphorylate Pyk2 in T cells [29].
The mechanism behind these differences has not yet been elucidated.
A switch activating estrogen receptors seems a plausible underlying mechanism causing these differences in expression.
However, the mechanism of these differences is not clear for the time being.
A possible mechanism for these differences is novel chemistry of hybrid host plants (Orians 2000).
However, the exact mechanism of these differences needs to be extensively investigated.
Although we could not determine the mechanism for these differences in patterns, several explanations may be considered.
Different immunogenetic associations in male and female patients with RA have been described previously [ 42- 46], although the mechanism underlying these differences is not fully understood.
One mechanism behind these differences is the disruption of the CpG dinucleotide motif recognized by DNA methyltransferase 1 enzyme (DNMT1) [ 15].
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