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These results demonstrate that forskolin suppresses insulin transcription in INS-1 cells through a PKA-independent mechanism that probably involves MAP kinase signalling.
After Miranda escaped from this resonance (through a mechanism that probably resulted in its anomalously high orbital inclination), its eccentricity would have been damped, turning off the heat source.
Furthermore, it is a revertible mechanism that probably does not imply mutations.
This is an advantageous mechanism that probably evolved to reduce the exposure to predators.
We can note this regulatory mechanism between immune circulating populations in stage III mechanism that probably compensates between the two arms of the immune response.
Taken together, we show here that allergic immune reactions are impaired in the absence of NCR1 through a mechanism that probably involves interaction of NK cells with DCs.
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Our analyses suggest that the activation/repression switch mechanisms that probably orchestrate the highly-biased expression of tissue-specific genes are generally not efficient on the X chromosome.
PPARδ increases apolipoprotein A-I and HDL synthesis by mechanisms that probably involve activation of the ATP-binding cassette transporter (ABCA1) gene [ 38].
These may function through direct ubiquination of the MHCII molecule itself or indirectly through mechanisms that probably involve ubiquitination of components of the endocytic machinery.
Moreover, elevation in plasma [Na+] can induce hypertension independently of EC fluid volume, through mechanisms that probably include stiffening of vascular endothelium [ 42- 46].
The results of this study also validate the concept that endogenous proteostasis mechanisms, mechanisms that probably protect ATD patients from hepatic proteotoxicity and disease, can be targeted for effective drug therapy.
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