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Competitive binding assays support the receptor-mediated mechanism of targeting.
However, the exact molecular mechanism of targeting is not fully understood; hence it warrants further investigation into the molecular mechanism.
The molecular mechanism of targeting has not fully understood for the inhibitory effects of AgNPs on the prostate cancer cells.
Although the mechanism of targeting of histone H3.3 deposition at specific loci in whole genome remains largely unclear, histone H3.3 has been considered as epigenetic regulator that is dispensable for proper expression of genes (Kato et al., 2015).
The identification of such cis-regulatory elements will in turn set the stage for subsequent studies to illuminate the underlying molecular mechanism of targeting.
It is possible that AEN escapes destabilization in the presence of both factors when it is present at low levels, but at high levels becomes sensitive to the stronger shutoff factor muSOX, due to a slightly different mechanism of targeting.
Similar(46)
Identification of GCS as an integral membrane protein of the Golgi complex poses questions concerning the mechanisms of targeting and localization of this enzyme.
The number and type of intrinsic and extrinsic natural mechanisms of targeting thrombin that have evolved validate thrombin as an important physiological target, and provide strategies to knock it out.
Based on our findings the mechanisms of targeting of PSGL-1 to the uropod may thus differ in lymphocytes and peripheral blood neutrophils.
However, the molecular mechanisms of targeting and covalent binding to a relevant host receptor have yet to be discovered.
Taken together we provide a simple and general mechanism for targeting of oligomers without the requirement of conformational-dependent epitopes.
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