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The exact mechanism of stem cell therapy in augmenting the function of ischemic cardiomyopathy is unclear.
We also isolated aligned cell pairs and measured their rate of reprogramming to stem cells to investigate the regulatory mechanism of stem cell formation.
To explore the process underlying this higher proportion of reprogrammed cells, we examined the inhibitory mechanism of stem cell formation in Physcomitrella by isolating two adjacent cells.
Dr. Lin's work is focused on the self-renewing mechanism of stem cells, using Drosophila germline stem cells, mouse germline stem cells, mouse embryonic stem cells, Hydra, and planarian stem cells as models.
These results would provide a positive reference for the application of these lanthanide-doped UCNPs as fluorescent nanoprobes for stem cell tracking to further understand the mechanism of stem cell fate in tissue engineering and stem cell therapy.
The multiple co-culture systems established in this study provide new methods for directing committed differentiation of stem cells as well as new in vitro models for studying differentiation mechanism of stem cells determined by a tissue-specific niche.
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High-throughput screening (HTS) of stem cells is widely used by the researchers in order to gain more insight in the underlying mechanisms of stem cell fate as well as identifying compounds and factors maintaining stemness.
Schultz, M. B. & Sinclair, D. A. When stem cells grow old: phenotypes and mechanisms of stem cell aging.
It is not yet known whether Snail acts in the mechanisms of stem cell migration.
These differences suggest that the regulatory mechanisms of stem cell formation from differentiated cells in Physcomitrella are distinct from those in ferns.
Extensive evaluation of the patient before and after transplant provides some insight into the potential mechanisms of stem cell mobilization and tracheal tissue regeneration.
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