Sentence examples for mechanism of specificity from inspiring English sources

Moreover, finding out the precise molecular mechanism of specificity involved in glucose control of protein degradation also remains a major challenge.

Our attempts to generate substrate-bound OTUD structures revealed an additional mechanism of specificity for OTUD2.

Base sequence recognition via local changes in backbone conformation is not unprecedented but is unusual as the sole mechanism of specificity.

Regulatory subunits often display a preference for one catalytic subunit isoform, yet the underlying mechanism of specificity remains to be elucidated.

To investigate the mechanism of specificity of the cAMP-response, we tested for the enrichment of various genomic features within the three subsets of CREB sites associated with fasting-induced, repressed, or non-responsive genes defined above.

We have now added a couple sentences regarding the mechanism to the Abstract, and we have also added a new section in the Discussion that goes into this in detail ("An alternate mechanism of specificity in the convergent apicomplexan LDH").

Further dissection of the mechanisms of specificity for P5 and ERp46 are essential for full understanding of their individual roles in recycling PrxIV.

As to non-orthodox R-M systems the absence of recognition site underrepresentation may be explained by a significantly shorter lifespan in bacteria due to efficient mechanisms of specificity changes, or less self-toxicity of such R-M systems.

Such additional mechanisms of specificity beyond effects on binding and catalysis may be important in vivo to minimize the remodeling of chromatin templates that do not, for example, have the correct modification status.

In spite of many studies on substrate specificity of nitrilases, the mechanism of substrate specificity has not been elucidated using structural and mutational analysis, except for study of the substrate specificity of arylacetonitrilase [ 14].

Inhibition of DAT does not, however, alleviate diquat toxicity suggesting an alternative transport mechanism lack of specificity for dopaminergic neurones, which was seen with NPC-derived midbrain cultures where diquat also killed GABA-ergic neurones.