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When these systems are embodied and situated in partially unknown environments, specific constraints arise for any neural mechanism of sequence generation.
RNA interference (RNAi) is an evolutionarily conserved mechanism of sequence dependent gene regulation that can have a role in host cell defense against intracellular pathogens and transposons.
The frequency and mechanism of sequence errors has been a subject of other studies.
This is very likely connected to 1) the molecular mechanism of sequence amplification and 2) differential initial growth capabilities in the different combination treatments.
Despite an extensive number of publications about MTB PhoP and its DNA binding, the consensus DNA sequence and the mechanism of sequence recognition remained obscure, thus preventing identification of direct targets of PhoP.
Interestingly, the genomic mechanism of sequence amplifications does not only contribute to antibiotic resistance evolution but also seems to represent a more general adaptive strategy of bacteria against highly stressful environments, as previously illustrated during carbon starvation, heat, or heavy metal stress (Andersson and Hughes 2009).
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The altered efficiency of transcription due to methylation of cytosines in the CpG dinucleotide sequence provides an important mechanism of sequence-dependent imprinting of genes [ 14].
RNAi is the mechanism of sequence-specific gene silencing by either the specific degradation of homologous mRNAs or transcription-mediated gene suppression (1- 4).
Following the first demonstration of siRNA-mediated gene silencing in mammalian cells [2], it was quickly realized that this highly specific mechanism of sequence-specific gene silencing might be harnessed to develop a new class of drugs that interfere with disease-causing or disease-promoting genes.
Transcription factors (TF) bind DNA in a sequence-specific manner and can have either a repressive or activating function, and recent work shows that sequence variants affecting TF binding sites are the underlying mechanism of sequence-specific gene regulation [ 1] that in turn can lead to altered histone modification states.
Fig. 8 Mechanisms of sequence termination.
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mechanism of sequential
mechanism of pattern
mechanism of pathway
mechanism of order
mechanism of nucleotide
arrangements of sequence
systems of sequence
mechanism of timing
mechanism of harmonisation
mechanism of infection
mechanism of radiation
mechanism of recognition
mechanism of er
mechanism of disease
mechanism of recovery
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