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This indicates that normal alleles up to 18 ATTCT repeats originated by a single step mechanism of repeat length mutation.
Surprisingly higher order Markov models are needed to explain repeats, as this was expected to be a feature of secondary structural elements, but this in fact simply reflects the mechanism of repeat expansion.
According to our knowledge, no estimate has been provided yet for the mutation rate of Y chromosome penta- or hexanucleotide STRs, although it is intuitively obvious that the figure should be lower than that of STR loci with smaller repeat unit sizes, since replication slippage, the mechanism of repeat count changes of STRs, is less likely to occur in case of longer repeats.
While Δ gna2 does not show a discernible phenotype, sporulation is increased in Δ gna3 and Δ rid1 is of particular interest, because in this mutant the mechanism of repeat induced point mutation (RIP) is likely to be perturbed.
The partial loss of elements seen in strains such as RF122 (Group 3) does not occur at this deletion site, and may represent a different mechanism of repeat propagation or an error in repeat translocation in an ancestral strain that has been maintained in subsequent generations.
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A relatively small portion (∼3.4%) of the genome is occupied by repeat sequences; however, the mechanism of repeat-induced point mutation appears active in this genome.
In addition, according to the shifting mechanism of repeating segments and the complementary based-paired nature in DNA double-stranded helical structures, several possible combinations of SSR patterns could be considered as an identical SSR motif within genetic loci.
The purpose of this study was to examine the elderly recidivist cohort at an urban trauma center for mechanisms of repeat injury.
The molecular mechanisms of repeat instability, regarding contractions and expansions, are mediated by DNA replication, repair and recombination, probably concerted [14].
This variation between species and between amino acids in the chi-squared values shows that there is considerable variation in the mechanisms of repeat expansion and selection between eukaryotes and suggest that lineage specific distributions of SAARs might be a general feature of eukaryotic evolution.
Molecular mechanisms of repeat removal in copepods remain unexplored.
More suggestions(15)
mechanism of recurrence
systems of repeat
mechanism of deposition
mechanism of infection
mechanism of recognition
mechanism of inhibition
mechanism of choice
mechanism of ultrasound
mechanism of comparison
mechanism of phase
mechanism of protein
mechanism of denial
mechanism of fear
mechanism of action
mechanism of oppression
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