Sentence examples for mechanism of mutation from inspiring English sources
In addition, the study recorded the mutation type evident in the cancer gene (somatic, germline, or both), neoplasm types associated with the gene (leukaemias/lymphomas, mesenchymal, epithelial, others), the phenotypic nature of the mutated gene (dominant or recessive), and the mechanism of mutation affecting each gene (e.g. translocation, deletion, frameshift).
To avoid the epistasis, a random mechanism of mutation of the genes should be introduced.
The differential evolution algorithm (DE) relies mainly on the mechanism of mutation, where an individual is perturbed using the weighted difference (with the so-called "scaling factor" F) between two randomly chosen individuals.
Nowadays, extensive attention has been paid to the leaf-color mutation, and certain achievements have been made by studying various organisms, but the mechanism of mutation and the responsible loci have not been fully understood at molecular level, especially in rice.
The VL1 locus in sIgM− cells was then sequenced to determine the mechanism of mutation.
These similarities suggest that the mechanism of mutation is conserved across species.
Thus, if we assume the ncDNA model for SZ, the remaining possibility is the mechanism of mutation-selection balance without heterozygote advantage.
The possibility of using VOCs as surrogate markers for genetic sub-types of lung cancer in situations where biopsies are unavailable for DNA sequence analysis is intriguing, but requires greater insight into the mechanism of mutation-driven VOC differences, if it is to be applied in a rational manner.
The pathogenic mechanism of mutations in the RRM1 domain is likely to be different.
The immunoglobulin gene diversification assay is used to determine the rate and mechanism of mutations that render DT40 cells unable to express surface immunoglobulin (sIg), thus reporting events in a specific, endogenous gene locus [39].
Taken together, these results collectively provide a more complete view of how several mechanisms of mutation, mutation repair, and bias act simultaneously to produce the net mutational patterns.
