Sentence examples for mechanism of ligand from inspiring English sources

In order to understand the mechanism of ligand binding and interaction between ligand and cyclin C, a 3D homology model for cyclin C is generated.

This review focuses on the analysis and interpretation of literature reports of studies of the rate and mechanism of ligand exchange reactions in hydrated organic solutions that are relevant to the separations of lanthanide and actinide metal ions.

The mechanism of ligand binding coupled to conformational changes in macromolecules has recently attracted considerable interest.

The above results all indicate that the mechanism of ligand binding to uranyl ions is sensitive to pH and the number of ligands involved.

The molecular mechanism of ligand binding to the ectodomain of these receptors and the resulting activation of their tyrosine kinase domain is still not well understood.

These results were provocative because they implied a mechanism of "ligand memory" by which different ligands could produce distinct NICD activities in the nucleus.

Despite this progress, to date, no high-resolution structure of a CNG channel in the closed and unliganded state is available, and therefore, the precise mechanism of ligand-mediated activation for this class of channels remains unknown.

Structural information is needed to elucidate the molecular mechanism of ligand-binding and receptor-activation of the 5-HT2c receptor.

Understanding the mechanism of ligand-assisted GQ folding is necessary for the design of more efficient cancer therapeutics.

Taken together, these studies provide information on the mechanism of ligand-binding to MAPKAPK2 that can be used in the search for selective small-molecule inhibitors.

The X-ray crystal structure of the human constitutive androstane receptor (CAR, NR1I3)/retinoid X receptor α (RXRα, NR2B1) heterodimer sheds light on the mechanism of ligand-independent activation of transcription by nuclear receptors.