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An extensive review on amylin was conducted eleven years ago by Kapurniotu which focused primarily on the morphological and structural features of amylin aggregates, mechanism of aggregation, and the effects of amylin on cell viability with a brief overview on the potential of N-methylated peptides as inhibitors of amylin-mediated cytotoxicity [ 13].
This section introduces a consistency mechanism of aggregation sessions for accurate aggregates.
Saelices, L. et al. Uncovering the Mechanism of Aggregation of Human Transthyretin.
These studies have focused on both the mechanism of aggregation and the identification of potential aggregation-prone sequence and structural motifs.
The mechanism of aggregation consists of the combination of charge neutralization, entrapment, adsorption and/or complexion with the coagulant ions to form insoluble precipitate.
Implications regarding the mechanism of aggregation of this peptide into fibrils and the role of the environment in modulating secondary structure are discussed.
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Furthermore, a self-assembly mechanism of aggregation-then-growth process through bubble template was proposed for the formation of the hollow hierarchical architectures.
The X-ray single structures and photophysical properties reveal that the mechanism of aggregation-induced emission in this class of fluorenone compounds is due to the formation of static excimers through hydrogen bonds in the solid state.
Scanning tunneling spectroscopy (STS) technique was used to study the piezofluorochromic mechanism of aggregation-induced emission (AIE) materials for the first time.
In addition, to gain insight into the mechanism of Aβ1 42 aggregation, aggregation models for Aβ17 42 (2 13 mer prepared at pH 7 8) were computed using a MMFF (molecular mechanics) method.
Although substantial progress has been made in the development of methods able to identify the species formed during self-assembly and to describe the kinetic mechanisms of aggregation, the structure(s) of non-native species, including potentially toxic oligomers, remain elusive.
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processes of aggregation
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