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This is exactly a switching mechanism in expression between correlation and inverse-correlation of two genes, controlled by another gene.
Thus, these observations reveal the possibility that the third interaction also may exist as the switching mechanism in expression of two genes, i.e. ATP5D and ITCH.
This issue can be a general, switching mechanism in expression of two genes, being controlled by categories of another gene, and finding this type of interaction can be a key to elucidating complex biological systems.
To confirm the reliability of the interactions in Table 4, we tried to find, for each gene pair, the switching mechanism in expression which can be controlled by some experimental condition of gene expression.
This directly indicates that there must exist a switching mechanism in expression between these two genes under the alteration of experimental conditions which is specified by the annotation of GDS2960_1.
Similar(55)
While expression and production have been fully developed and Chinese hamster ovary cells are used for the majority of products both on the market and in clinical development, significant progresses in developing and engineering new cell lines, introducing novel genetic mechanisms in expression, gene silencing, and gene targeting, have been reported in the last several years.
DNA methylation is an essential regulatory mechanism in gene expression.
Alternative polyadenylation as a mechanism in gene expression regulation has been widely recognized in recent years.
This in turn suggests that the stress-regulated miRNAs such as miR399 and miR827 may share a common mechanism in both expression and function.
Alternative polyadenylation (APA) represents a common and critical regulatory mechanism in gene expression that involves the use of different PA sites for one and the same transcript.
This study showed that splicing-level regulation is a fine-tuning mechanism in the expressions of specific proteins.
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