Sentence examples for mechanism for activating from inspiring English sources

TTS toxins use a unique mechanism for activating their enzymatic activities.

Furthermore, it has also been suggested that Rho GTPases are regulated by a fine balance between GEF and GAP activities, and that the inactivation of GAP activity is a physiologically important regulatory mechanism for activating Rho GTPases [ 19].

These domains interact when the enzyme is in the inactive conformation, and the V600E mutation shifts the kinase into the active conformation, suggesting that disrupting this interaction is a primary mechanism for activating the BRAF oncogenes.

Phosphorylation is a common mechanism for activating proteins within signaling pathways.

An activating mutation at codon 600 converting valine to glutamic acid (V600E), is another mechanism for activating BRAF without upstream RAS phosphorylation in LGG.

We previously found that ATP was released extracellularly by PMNs through pannexin-1 (PANX1) hemichannels and that autocrine feedback through the P2Y2 receptor, one of eight P2Y G protein-coupled receptors, is an essential mechanism for activating PMNs [5, 6].

The best-studied mechanisms for activating mTORC1 and protein synthesis are via receptor tyrosine kinase activation by growth factors such as insulin-like growth factor (IGF -I and IGF -In (36) and nutrinsulin activation by branched-chain amino acids (36).

This suggests that there might be alternative mechanisms for activating soxS expression in the conditions tested (which were different from conditions used for the micoarray experiment).

Clearly, the wide diversity of sigma factors and transcriptional regulators in C. metallidurans CH34 points to intricate regulatory mechanisms for activating genes in response to environmental stimuli.

Knowledge of the genetic abnormalities present in pediatric LGAs is limited, though recent studies have identified BRAF translocations, chromosomal duplications, and occasional base mutations in low-grade astrocytomas[18], [25], as well as diverse mechanisms for activating the ERK/MAPK pathway in pilocytic astrocytomas [23].

Indeed, intact talin binds vinculin with low affinity (Patel et al, 2006); the mechanisms for activating the vinculin-binding sites in the talin rod remain to be determined.