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Thus, a helix replacement mechanism directs metavinculin's unique functions.
Xist spreads from this locus, and through a still relatively unknown mechanism directs the heterochromatinization and subsequent silencing of gene expression from the Xist-expressing chromosome [ 60].
This lateral inhibition mechanism directs binary fate decisions in many species and developmental contexts, including neurogenesis in Drosophila (Ruohola et al., 1991), development of the inner ear and the intestine in vertebrates (Cotanche and Kaiser, 2010; Crosnier et al., 2005; Haddon et al., 1998a; Heath, 2010), and development of the vertebrate vasculature (Gridley, 2010).
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I am not working on curing a particular disease but on understanding how the basic mechanism directing cell migration works.
Studies suggest a nick-directed mechanism using Okazaki fragments produced during replication of the lagging strand or a strand discrimination mechanism directed by the proliferating cell nuclear antigen (PCNA), thus coupling replication and MMR [2], [11].
There are several mechanism directing the protective effects of H2S.
This dual promoter mechanism directing expression of murine isoenzymes is not conserved in humans.
The reduced regulatory information in the promoters of ribosomal proteins might be compensated by the translational regulation mechanism directed by the 5' terminal oligopyrimidine sequence in their mRNAs [ 45].
The mechanism directing the latter has attracted attention in recent years due to the importance of this type of mutation in diseases such as schizophrenia and autism.
Mechanical damage activates diverse mechanisms directed to healing and defense [ 19].
Knowledge of mechanisms directing diarthrodial joint development may be useful in understanding joint pathologies and identifying new therapies.
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