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You then turn the pin, which activates the mechanism, and opens the secret compartment.
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This results help to confirm the validity of the proposed mechanism and open up the possibility of developing novel mechanism based inhibitors specifically for this target.
The fact that it only induces Fas/Fas L increase in the cells where it has cytotoxic effects emphasises that this is the mechanism involved and opens the possibility that the cytotoxic effects of melatonin in other cancer cell types may also be due to the regulation of death receptors and/or their ligands.
The results open new insights into previously undisclosed pathogenic mechanisms and open the potential for biomarker discovery and therapeutics that may influence the course of HIV-1-mediated neurodegeneration.
These research activities will propel our understanding of diseases and their origins and mechanisms, and open up opportunities for prevention and treatment.
Given the known effects of fusel alcohols targeting eIF2B in S. cerevisiae, these results are entirely consistent with the presence of a similar mechanism in C. albicans and opens up the possibility that such a regulation could be involved in morphogenetic alterations and pathogenicity.
This study brings new insights in the DLC growth mechanisms in confined nanospaces and opens new avenues to fabricate hybrid, chemically resistant and biocompatible carbon-coated nanoarchitectures on other inorganic supports.
The present work further aids the understanding of the underlying mechanisms leading to tinnitus and opens the path for the development of new pharmacotherapies.
Nonetheless, the promoters of these MMPs share many common cis-regulatory elements that may respond coordinately [ 6- 8]; the present report of differential regulation sheds new light on the mechanisms regulating MMP-3 expression and opens up the possibility of developing targeted therapies directed at MMP-1 or MMP-3.
The findings offer insights into the design of crisis management mechanisms and open areas for further research.
As stress-induced starch exhaustion impairs growth, identification of the ABA-responsiveness of the starch breakdown machinery now enables the identification of novel regulatory components/mechanisms and opens up new perspectives for improving yield and biomass production under unfavourable environmental conditions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com