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This aim is even more crucial in the process of rational design of biomaterials with selected mechanical properties, in which not only the mechanics of single molecules but also of their assemblies has to be cared of.
Rief, M., Clausen-Schaumann, H. & Gaub, H. E. Sequence-dependent mechanics of single DNA molecules.
Lintz, M., Muñoz, A. & Reinhart-King, C. A. The Mechanics of Single Cell and Collective Migration of Tumor Cells.
Kojima, H., Muto, E., Higuchi, H. & Yanagida, T. Mechanics of single kinesin molecules measured by optical trapping nanometry.
Studies into the mechanics of single cells, subcellular components and biological molecules have rapidly evolved during the past decade with significant implications for biotechnology and human health.
Here we review cellular mechanics of single cells in the context of epithelial cell layers responding to chemical and physical stimuli.
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This chapter discusses the methods that have been used to study the mechanics of single-molecule DNA and RNA.
Although we used the force sensor to characterize mechanics of single-layer cell sheets and silk fibers, the design can be easily adapted for different applications spanning larger force ranges (>N).
To further understand the mechanics of single-nanoparticle detection, investigators have also been studying the specific details of plasmonic nanostructures that are responsible for their use in sensors such as the distance dependence of sensitivity and the resonant electric field enhancement distribution.
The micro-mechanics of single molecules studied with atomic force microscopy.
The researchers observe that two different but related reactions respond to force in pretty much the same way--that is, the mechanism of the reactions is reflected in the mechanics of the single molecules.
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