Sentence examples for mechanically regulated from inspiring English sources

We propose that primary cilia are also important in mechanically regulated bone formation in adults and that their malfunction could play a role in complex multi-factorial bone diseases, such as osteoporosis.

When taken together these results suggest that tamoxifen decreases LOX, LOX-L2 and fibronectin expression via HIF-1α, and that the effect of tamoxifen on HIF-1α levels is mechanically regulated by reducing myosin-2 dependent HSCs contractility and tissue stiffness.

As expected, scleraxis expression is mechanically regulated, showing a reduction following tendon transection 9 and exhibiting a dose-response with increasing strains or repetitions of movement.

While dystrophin deficiency does not directly affect bone and cartilage growth, the growth of these tissues is mechanically regulated and therefore indirectly affected by strains from muscle contraction [ 11].

To implicitly describe the latter and its effects on the intracellular domain, we use mechanically regulated protein synthesis.

Multiple response mechanisms would be advantageous in terms of biological redundancy or may be associated with distinct mechanically regulated functions, such as turnover or repair.

We suggest that HIF-1α may act as a converging point to mechanically regulate the adaptive response of HCC to hypoxia and the overall architecture of the tumour microenvironment.

Our hypothesis is that transmembrane receptors like integrin might be affected mechanically by the micro-ranged geometry of the titanium surfaces, and successive biochemical spatial-temporal mechanisms regulate actin polymerization locally.

Parts of the screen will open and close mechanically to regulate the light, further breaking down the facade's uniformity and hinting at the busy and varied activity taking place inside.

If this model is correct, it is obvious that the ability of a sensory neuron to become sensitized to mechanical stimuli, or indeed to become newly mechanically sensitive, can be regulated at the levels of vesicle transport, fusion, or endocytosis of, or recovery of, spent transduction complexes (Fig. 1A).

It has been well recognized that skeletal muscle mass is regulated by mechanically induced changes in protein synthesis, and that signaling by mTOR is necessary for an increase in protein synthesis and the hypertrophy that occurs in response to increased mechanical loading.