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High FiO2 and PEEP, both leading to high PaO2 values, may delay weaning from mechanical ventilation, thus negatively influencing outcome in ICU patients.
In most of the studies reviewed patients bridged with ECMO were also supported with mechanical ventilation, thus combining two invasive means of respiratory support, each with potentially harmful side effects.
The findings of the present study suggest that pretreatment with metformin prevented increases in pulmonary microvascular permeability in response to injurious mechanical ventilation, thus attenuating VILI in terms of edema formation and histology.
Prior clinical trials of several pharmacologic agents in ALI may have failed to improve outcomes in part because the trials enrolled patients who already required mechanical ventilation, thus delaying initiation of therapy until several days after the onset of lung injury.
Similar(56)
Postoperatively, four patients remained on mechanical ventilation and thus no "PACU" measurements are available.
Mechanical ventilation may thus be expensive compared to n-BiPAP due to the need for more intensive monitoring and care.
Providing optimal mechanical ventilation is thus an essential part of the care of very low birth weight infants.
Indeed, the longer duration of mechanical ventilation and thus ICU stay in our study in ABDC-treated patients can be explained by pulmonary adverse effects of the drug.
Thus, mechanical ventilation was used in 132 patients, of whom 90 survived and 42 died.
Thus, mechanical ventilation synergizes with systemic and intratracheal LPS in the induction of acute lung injury.
Thus, mechanical ventilation may exacerbate the pulmonary pathology and/or delay recovery.
Related(11)
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