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The average of mechanical ventilation previous to exposition to SBT was 7 days for the NPPV group and 8 days for the IMV group.
The factors which were significantly associated with multidrug resistance include the recovery of Acinetobacter from multiple sites, mechanical ventilation, previous antibiotic use, and the presence of co-morbidity (especially neurologic impairment).
The factors associated with multidrug resistant isolates in this study were mechanical ventilation, previous antibiotic use, neurologic impairment, and the recovery of Acinetobacter from more than one anatomic site.
The factors associated with the isolation of AB in our combined medical and surgical patient groups include mechanical ventilation, previous antibiotic therapy, co-morbidity, especially neurologic impairment, and multiple Acinetobacter isolates.
We evaluated sex, age, associated co-morbidities, laboratory test results and main diagnosis at ICU admission, hours in conventional mechanical ventilation previous to HFOV connection, indication of HFOV, laboratory test results at the connection time to HFOV, and patient outcome.
The factors which were found to be significantly associated (p ≤ 0.05) with multidrug resistance include the recovery of AB from multiple sites, mechanical ventilation, previous antibiotic exposure, and the presence of neurologic impairment.
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Risk factors for MRB were pulmonary source, mechanical ventilation and previous infection by the same bacteria.
At SAT initiation, patients with IC exhibited a lower SOFA score, and had less often septic shock, invasive mechanical ventilation, and previous corticosteroid treatment, whereas surgery just before or during ICU stay was more often present.
We concluded that mechanical ventilation and previous exposure to imipenem/meropenem were independent risk factors for MDRP infections, while mechanical ventilation and antibiotic resistance switch were predictive factors of outcomes of MDRP infections.
Adverse prognostic factors include the number of organ failures, invasive mechanical ventilation and previous bone marrow transplantation.
The history of mechanical ventilation in previous breaths and the applied PEEP level strongly determine the working envelope in the present breath and the chances of promoting intratidal recruitment during mechanical ventilation in ARDS patients.
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