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PCV for ARDS patients is associated with lower peak airway pressures, a more homogeneous gas distribution, improved patient-ventilator synchrony and earlier liberation from mechanical ventilation compared to volume-controlled ventilation [25, 26].
Dexmedetomidine also led to a reduction in duration of mechanical ventilation compared with midazolam but not compared with propofol.
Low CSCI patients with early tracheotomy also had significantly less days on mechanical ventilation compared to those with late tracheotomy (12.1+/-10.4 and 25.2+/-17.7; p = 0.034).
In contrast, in LPN patients, Casaer reported a relative reduction of mechanical ventilation duration (9.7%) among patients requiring ≥2 days of mechanical ventilation compared with EPN [13].
Recently, a protocol of no sedation has shown reduced duration of mechanical ventilation compared to daily interruption of sedative infusion, without severe adverse events [9].
Conclusions: Among patients with MA and COPD or OHS, early treatment with ACTZ shortened not significantly the duration of mechanical ventilation compared with placebo.
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Several investigations have shown that very old patients admitted to the ICU receive less aggressive treatment, including mechanical ventilation, when compared with younger cohorts, despite comparable illness severity scores [ 13, 15, 16].
In our study, these children were more likely to sustain serious/severe TBI and had significantly higher rates of ICU admission and mechanical ventilation when compared to children hospitalized with TBI due to other types of falls.
In immunocompromised patients admitted to ICU for acute hypoxemic respiratory failure, High-Flow Oxygen was associated with lower intubation and mortality rates, and a reduced duration of invasive mechanical ventilation as compared to O2 or NIV.
In data collected during the Third International Study on Mechanical Ventilation, we compared data from the Netherlands with a global cohort.
Continuous intravenous sedation, for example, is associated with prolonged mechanical ventilation as compared with sedation via intermittent boluses [ 43].
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