All the patients underwent mechanical ventilation, catecholamines levels were 0.4 (0–6.4) mg/h, and lactate levels was 2.3 (1.5–3) mmol/l.
Patients were more likely to receive antithrombin if they had severe burns, a higher burn index, and more requirements for mechanical ventilation, catecholamines, and other treatments, according to comparisons between unmatched groups.
The baseline patient characteristics in the unmatched groups suggested that antithrombin use was higher in patients with severe burns (e.g. those with higher mortality and higher burn index and those requiring mechanical ventilation, catecholamines, and other treatments).
After surgery, our animals remained under general anaesthesia and received maximal critical care support, including mechanical ventilation, catecholamines, diuretics, and other medication if required.
We observed that, indeed, hypoglycemia was associated with increased ICU length of stay and use of mechanical ventilation, catecholamines and renal replacement therapy, even when we adjusted for initial severity (Tables 3 and 4).
Organ support including mechanical ventilation, catecholamine infusion and, renal replacement therapy were respectively used in 58, 45, and 20% patients.
We included following parameters in the analysis: sex, scheduled surgery, unscheduled surgery, medical admission, mechanical ventilation, catecholamine therapy, renal replacement therapy, age, pH, leukocytes, creatinine, bilirubin, and hemoglobin.
Organ support including mechanical ventilation, catecholamine infusion, renal replacement therapy and veno-arterial ECMO were used in 34, 31, 11, and 12 patients, respectively.
Mechanical ventilation, catecholamine and arrhythmia occurred in 60 (31%), 132 (68%) and 154 (79%) of the measurements.
Predefined endpoints were 30-day mortality and the combined endpoint critical pneumonia, defined as presence of death occurring during antibiotic treatment, mechanical ventilation, catecholamine treatment or ICU admission.
The following clinical characteristics were recorded: age, gender, Simplified Acute Physiology Score II (SAPS II) on admission, reason for admission to the ICU, previous significant disease, intubation and mechanical ventilation, catecholamine infusion, and extra-renal procedures.
