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Exact(27)
It is also possible that the extended duration of mechanical ventilation alone was enough to cause ventilator-induced lung injury (VILI) without an additional effect of tidal volume size.
It is known that high tidal volume ventilation causes VILI after acid instillation in rats [29]: however, to show that this model was more injurious than prolonged mechanical ventilation alone, rats treated with sterile saline instead of hydrochloric acid and mechanically ventilated for 5 h were used as control.
Confined spaces may be entered without the need for a written permit or attendant provided that the space can be maintained in a safe condition for entry by mechanical ventilation alone, as provided in § 1910.146(c)(5).
Testelmans et al. [32] Rat / 34 Prospective Randomize N/A N/A Y Y 24 hours of NMBA associated with increased CIM than mechanical ventilation alone.
Severe cases of ARDS with life-threatening hypoxemia or hypercapnia can undergo extracorporeal membrane oxygenation (ECMO) or pumpless extracorporeal lung assist (pECLA) as a rescue therapy, when conservative treatment strategies such as prone positioning are exhausted and oxygenation cannot be maintained with conventional mechanical ventilation alone.
In a recent metaanalysis, Wurfel [48] has indicated that across the different experiments, the most clearly overrepresented theme was "responses to pathogens", noting that the selected genes for the final analyses were identified as differentially regulated in the presence of injury by mechanical ventilation alone.
Similar(33)
In the sickest of these patients, mechanical ventilation (MV) alone may not be sufficient to establish adequate gas exchange.
Patients did not receive other drugs, except antibiotics (for all of them) and sedative drugs for those receiving mechanical ventilation (propofol alone or in combination with fentanyl or remifentanyl).
Current guidelines indicate that NMBA are appropriate for facilitating mechanical ventilation when sedation alone is inadequate, most notably in patients with severe gas-exchange impairments, like in patients with ARDS [4].
Current guidelines indicate that NMBA are appropriate for facilitating mechanical ventilation when sedation alone is inadequate, most notably in patients with severe gas-exchange impairments, like in patients with ARDS [ 4].
A PubMed search of the terms "Airway Pressure Release Ventilation", "APRV", "Bi-Vent", "APRV/Biphasic" and "Bi-Level" and "Mechanical Ventilation" OR "Ventilator" was conducted alone or in combination.
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