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Mechanical threshold of muscle input ranged from 8.8 to 14.7 mN (mean temporal muscle 12.7 mN, neck muscles 13.6 mN).
The CFD model was employed to simulate the τMSS which will most probably exceed the mechanical threshold of the nociceptors, τth.
To observe how different treatments affect the allodynia, behavioral tests were performed 1 d before the drugs administration to provide baseline scores, and then from 4 h after SNL and for 1 w (once a day) to evaluate the gradual changes in the mechanical threshold of the rats.
The mechanical threshold of each recorded joint afferent was determined by a gradual increase of torque to the joint until the fiber started to elicit action potentials.
The mechanical threshold of the animals in the control (C) group was also examined and compared using repeated-measures analysis of variance.
This myelinated HTMR fiber had a mechanical threshold of 10 mN and neither a 5 mN mechanical stimulus nor the maximal intensity of blue light evoked a response.
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Combining this method with a local coefficient of friction, which is determined using a mechanical threshold on the protective nature of the lubricant, and a strain related failure to model the smoothening of surfaces protected by a lubricant, the surface topography can be calculated.
Neurons were also sensitized by this treatment showing decreased mechanical thresholds of the dural receptive sites and enlarged facial and cervical cutaneous mechanoreceptive fields as well as increased responses to noxious mechanical stimulation of paraspinal muscles [43].
However, analysis of the mechanical thresholds of C- fibers did suggest that a subpopulation of C- fibers was somewhat influenced by rapamycin (Fig. 7) and indeed the expression of raptor overlapped with non-N52 positive profiles in the sciatic nerve.
Modulation of RA currents by external Ca2+ is distinct in capsaicin-sensitive and insensitive neurons [9] and the mechanical thresholds of the two cell types are different, implying that distinct ion channels may mediate RA currents in nociceptors and non-nociceptors.
In addition, mechanical thresholds of the subjects were measured to determine whether cupping has an effect on mechanical hyperalgesia in patients with chronic neck pain.
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