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Fibroblast attachment to collagen bundles occurred at numerous points (indicated by the presence of multiple focal adhesions) and the cells showed a high degree of mechanical stress (indicated by actin stress fibre formation).
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Such excellent stabilities against thermal and mechanical stresses indicate that FeCrAl foam is a good candidate for catalyst supports under thermally and mechanically harsh environments.
On the other hand, the level of cytotoxicity of CisPt on HepG2 cells increased in the presence of carnosine and mechanical stress as indicated by the decrease in cell viability.
It was previously shown that OPN-/ mice did not suffer bone loss in response to mechanical unloading [ 120], suggesting that mice lacking Spp1 could not sense the changes in mechanical stress, thus indicating its potential role in the signal transduction of mechanical stimulation.
These results suggest that osteoblastic differentiation of D1 cells is promoted if suitable mechanical stress is provided, which indicates biological relevance of the bone regenerative properties of this material under mechanical stress that were shown in a previous in vivo study.
In addition, in comparison with that of the wild type, chalky tissues of DY1102 are easily broken under the mechanical stress during sample preparation, indicating differences in chemical composition or microstructure of the chalky tissue between DY1102 and its wild type.
Tissue amphiregulin levels were not different between AP318 and CTRL group, indicating that mechanical stress was similar between both groups and that AP318 did not protect the lung from mechanical stress.
However, as the data summarised in Table 1 clearly indicate, reducing mechanical stress by releasing the collagen lattice from the plastic dish is not sufficient, in and of itself, to promote tube formation.
The upgoing expressions of those markers indicate that mechanical stress is vital not only in the early stage of osteogenesis but also in the later stage of tooth and bone formation.
They found a strong positive linear correlation (r = 0.75) between mechanical stress and tumor cell death, as indicated by the shape of the tumors.
This also indicates that normal mechanical stress may not stimulate cell replication as demonstrated in previous studies [ 34].
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Justyna Jupowicz-Kozak
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