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To determine whether mechanical stress alone is able to activate JNK/SMAD2-L signaling, we performed muscle stretch experiments.
Moreover, the application of mechanical stress alone or in combination with either CisPt or PBMCs was also effective in destroying cancer cells, though to a slightly lesser extent.
Therefore, it can be explained that mechanical stress alone is possible to initiate OA development without the stimulation of proinflammatory cytokines.
Only when CisPt was combined with PBMCs were cancer cells destroyed below control levels, but this was not different from the activity of mechanical stress alone.
This agrees with the current study's finding that mechanical stress alone can statistically reduce cancer cell survival to 55% compared to the control group.
Cell survival for mechanical stress alone was 55%, which was statistically lower than control, but was not statistically different compared to any other test group.
Similar(49)
Cell morphology was visualized by F-actin fluorescence staining to determine the effect of heating and mechanical tensile stress alone or in combination.
The tectonic pull from the west puts the entire mountain range under mechanical stress and one quake alone is not enough to release all of the tectonic loading.
Yu X, Guo Y, Kang Q, Luo C. Effects and mechanisms of mechanical stress on secondary fracture healing.
When combined with CisPt alone, PBMCs alone, or CisPt + PBMCs, mechanical stress further statistically reduced cancer cell survival.
Cell survival rate for mechanical stress + CisPt + PBMCs was only 29%, which was statistically lower than control, CisPt alone, PBMCs alone, or CisPt + PBMCs, but it was not statistically different from any of the other test groups involving mechanical stress.
More suggestions(15)
mechanical heterogeneity alone
mechanical dispersion alone
mechanical anisotropy alone
mechanical abrasion alone
mechanical load alone
mechanical testing alone
mechanical debridement alone
mechanical therapy alone
mechanical ventilation alone
mechanical cutting alone
mechanical strain alone
mechanical stimulus alone
mechanical loading alone
mechanical loosening alone
mechanical deformation alone
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