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Exact(19)
Inactivity has a profound effect on the bone tissue, probably because the mechanical stimulus to bone formation is decreased.
To report four subjects with a combination of floppy eyelid syndrome, mental retardation, and increased mechanical stimulus to the affected side.
Specifically, it relates the mechanical stimulus to the change in Hounsfield Unit (HU) value in terms of surface area density (SAD) of bony morphology, which allows direct correlation to clinical computerised tomography (CT) data.
Currently, much research effort is being expended on applying mechanical stimulus to the physical environment in which cells and tissues are being incubated and guided into the desired phenotype.
Flexural deformation has been used for the biomechanical characterization of native and engineered cartilage and as a mechanical stimulus to induce alteration of cartilage shape during in vitro culture.
Bohm et al. [31] suggested that the short loading duration during jumping constrains the transduction of the mechanical stimulus to the cellular level due to the viscosity of the tendinous tissue and, therefore, may not be optimal to facilitate adaptive responses of the tendon.
Similar(41)
The mechanisms and components by which osteocytes convert mechanical stimuli to biochemical signals are not well known.
Nociceptors respond to dangerously intense mechanical stimuli, to mechanothermal stimuli or to thermal and chemical stimuli.
This work demonstrated the use of electrodeformation, which is defined as whenever a dielectric forces (DEP) was utilized to apply mechanical stimuli to deform a cell [71].
Tissue engineering scaffolds provide temporary mechanical support for tissue regeneration and transfer global mechanical load to mechanical stimuli to cells through its architecture.
One particular challenge lies in the delivery of functional mechanical stimuli to implanted cell populations to activate and promote osteogenic activities.
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