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A mechanical stimulus on detrusor tissue is critical to bladder outlet obstruction progression and functional bladder tissue engineering.
For the comparison, 2D maps of the average bone formation and peak mechanical stimulus on the tibial endosteal and periosteal surface across the entire cortical surface were created.
According to Li et al. [91], positive density was illustrated deeper to the implant surface which may be due to the mechanical stimulus on the favorable cancellous bone.
We used a mechanical stimulus on the glottis with the thin nylon fiber (diameter 0.2 mm) in order to induce ERg.
To examine the effect of mechanical stimulus on PER2 expression, we used a mild stimulus, as in other studies (36), by inverting the vial 3 times.
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Besides this, also minor involvement of mechanical stimuli on the mechanisms controlling arterial vasodilatation in muscle is discussed like the ATP release from red blood cells by deformation or the NO release from endothelia cells by shear stress (Sarelius and Pohl 2010).
Presently, little is known about the simultaneous regulation of mechanical vibration, especially at acoustic frequencies, on osteogenesis and adipogenesis of BM-MSCs, which significantly limits our understanding of the role of the mechanical stimuli on this critical osteoporotic mechanism.
Generally, the tissue engineering studies investigated the effect of mechanical stimuli on cultivated constructs at least in one study arm compared to unstimulated controls (Darling and Athanasiou 2003; Mauck et al. 2003).
However, the effects of mechanical stimuli on engineered cartilage may vary substantially between different scaffolds.
Next, the effects of mechanical stimuli on chondrocyte biosynthesis and pathological changes in SF composition are covered.
A mechanoregulation theory based on scaffold shear strain and fluid shear stress was applied for determining the influence of each structures on the mechanical stimuli on initial conditions.
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