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However the mechanisms by which cell shape influences the response of the ECM microenvironment to mechanical loading is yet to be elucidated.
Mechanical loading is important in disease progression and treatment.
Single-crystal MgO under mechanical loading is modeled and simulated.
Abnormal mechanical loading is one of the major factors causing disc degeneration.
Mechanical loading is thought to be one of the most important environmental factors, affecting bone status.
Mechanical loading is a potent regulator of skeletal size, shape, internal architecture, and composition.
Sugiyama, T. et al. Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition.
In the two first cases, the aging of pure resin specimen, under mechanical loading, is analyzed.
While bone mass and geometry are largely genetically determined, mechanical loading is considered to be an important additional determinant.
Chondrocyte deformation, which occurs during mechanical loading, is thought to play an important role in the mechanotransduction pathway.
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Its behaviour under hydro-mechanical loading is essential to the safe design of the whole storage system.
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