Assuming that this asymmetry is the result of tennis participation, it could reflect either a greater adaptation to highly asymmetrical mechanical load (even more than that observed for the arm muscles) or less likely that the rectus abdominis has a greater potential for hypertrophy than the muscles of the arm.
However, the decline in systemic estrogens in primates did not result in changes in the response of the patellar tendon or ACL to mechanical load even after two years, which suggests that postmenopausal reductions in serum estrogens in primates also may not influence homeostasis of connective tissues of the knee equally.
With this level of thickness, it is possible to create interesting tribological systems with high mechanical load carrying capacity even on softer steels, which are used in general engineering.
Even though search about ECM response to mechanical loading and the mechanism in what manner it occurs on masticatory muscle are scarce, the changes in teeth occlusion may interfere in turnover of extracellular matrix (ECM).
Other potential mechanisms include cumulative mechanical loading and micro-trauma and proprioceptive deficits.
These findings will help more accurately model the cellular mechanical environment in mesenchymal tissues, which could assist in describing injury thresholds and disease progression or even determining the influence of mechanical loading for tissue engineering efforts.
It may even improve its efficiency during mechanical loading tests.
In vitro studies confirm that mechanical loading of cartilage stimulates cell division and matrix synthesis [ 31, 32], even in the moderate range of 10 MPa [ 33, 34].
Such cells may alter their orientation, shape, internal constitution, contraction, migration, adhesion, synthesis and degradation of extracellular constituents, or even their life cycle in response to perturbations in mechanical loading (Zhu et al. 2000).
In conclusion, our results demonstrate that concerning the mass, structure, and mechanical competence of rat bones, the homeostatic loading-driven regulatory feedback system maintains its capacity to respond to increased exercise loading even into very old age.
