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Special attention is given to tissue deformation under mechanical loading at different length scales.
It is generally accepted that mechanical loading at physiologically low levels stimulates the biosynthesis of extracellular matrix (ECM) macromolecules5 to improve the mechanical and biochemical properties of engineered cartilage neotissues6,7.
This paper describes a biomechanical investigation of heel ulcers using a theoretical model that characterizes the internal mechanical loading at the soft tissues of a supported heel.
Two laboratory examples provide evidence for (1) adsorption-induced swelling stress during constrained CO2 adsorption and (2) desorption upon mechanical loading at constant CO2 pressure.
The GAG synthesis (at the cell level) was coupled with the mechanical loading (at the tissue level) via a cell-matrix unit approach which established a relationship between the variation of cell dilatation and the local tissue dilatation.
The model is important to understand the effect of mechanical loading at the tissue level on GAG synthesis at the cellular level, as well as to optimize the mechanical loading in growing engineered tissue.
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We studied fluctuations in the displacement of silica beads driven by single molecules of the motor protein kinesin, moving under low mechanical loads at saturating ATP concentrations.
Typically, an SMP is pre-deformed from an initial shape to a deformed shape by applying a mechanical load at the temperature TH>Tg.
Increases in the external knee adduction moment (EKAM) have been associated with increased mechanical load at the knee and progression of knee osteoarthritis.
The aim was to characterize the magnitude and pattern of mechanical load at the knee and on the patellar tendon during four types of eccentric squat.
First, the influence of the geometry of the bonded assembly close to the free edges of the adhesive on the stress state under a mechanical load at a given temperature is analysed with a 2D numerical analysis.
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