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Mice were randomly divided into two test groups: a control to which a mechanical load was applied to the left knee without drug treatment and a mechanically loaded group treated with celecoxib.
Free-end deflection of a composite plate with different location of mechanical load was studied analytically and experimentally.
Static analysis of functionally graded, transversely isotropic, and magneto-electro-elastic circular plate under uniform mechanical load was discussed by Li et al. (2008).
Inhibition of the PKA-independent cAMP-mediators Epac1 and Epac2 with HJC0197 resulted in enhanced cartilage formation, which was additive to that of the mechanical stimulation, implying that the chondrogenesis-promoting effect of mechanical load was independent of Epac.
The application of a repetitive mechanical load was initiated via the implants (50 N, 3 Hz, 1800 cycles, 2 days/week) at 12 weeks after surgery for 8 weeks.
Mechanical load was applied in a custom-made bioreactor, previously described by Kim and Mooney [ 68].
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OA is a multi-factorial disorder - age, genetics and mechanical load are all contributing factors; the underlying molecular mechanisms are still largely unknown.
The loading-related biochemical responses (intracellular G6PD activity and NO release) to mechanical load were also determined.
As mechanical load is applied, the rotor slips back a number of degrees with respect to the rotating field of the stator, developing torque and continuing to be drawn around by this rotating field.
Mechanical load is stated for accidental design situation.
In the second case, a mechanical load is applied.
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