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It is well established that mechanical load affects bone cells.
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It remains to be determined in what way the acute or delayed onset of signaling pathways in response to mechanical load affect the balance between protein synthesis and degradation, and whether such responses are fiber-type specific.
In heart valve tissue, it is unclear to what extent mechanical loading affects the collagen fibril morphology.
Mechanical loading affects local bone mass and architecture in vivo by initiating a cellular response via loading-induced flow of interstitial fluid.
The objectives of this study were to determine: (i) if GFP reporters expressed in the TMJ indicate the different stages of cell maturation in fibrocartilage and (ii) how mechanical loading affects cellular response in different regions of the cartilage.
However, mechanical loading affects the bone formation with growth factor signaling in a clinical setting [ 9].
This work shows how these mechanical loads affect lithium-ion cells.
Conventional concrete and fiber reinforced concrete has brittle nature and hence crack easily under environmental and mechanical loads affecting durability of structures.
Several studies using cartilage explants or chondrocytes seeded in three-dimensional (3D) scaffolds have shown that mechanical compressive loading affects the chondrocyte metabolic activity [ 1- 10].
In vitro studies have shown that such mechanical loading significantly affects terminally differentiated cells as well as lineage commitment in undifferentiated multipotent stem cells [3], [26] [44].
These results demonstrate that mechanical loading directly affects immediate early BMP signalling events.
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