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OA is a disease affecting articular cartilage and the underlying bone, resulting from many biological and mechanical interacting factors which change the extracellular matrix and cells and lead to increasing levels of cartilage degeneration.
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But must we represent only inorganic nature — stones, stars, nebulae, planets, billiard balls — as a set of mechanically interacting mechanical systems, or earth's plants and animals as well?
Most recently introduced devices utilize vibrating resonant mechanical structures interacting with the fluid where the resonance frequency and the quality factor are affected by the fluid's viscosity.
It is expected that future applications of robotic manipulators will require the skilled use of multiple mechanical systems interacting with the environment in more flexible and powerful manners than those allowed by a single device equipped with a standard end effector.
The chronically inflamed rheumatoid synovium is a complex environment with various cellular subtypes, cytokines, growth factors, chemokines, proteases and mechanical phenomena interacting with each other over time.
The aim of this study was to explore how cell matrix interactions and extrinsic mechanical signals interact to determine stem cell fate in response to transforming growth factor-β3 (TGF-β3).
To investigate whether phosphorylated PKCδ by mechanical stress interacts with BR-Smads, we next performed Glutathione S-transferase (GST) pull-down assay.
Currently, we are beginning to understand how different types of contractile activity and mechanical loading interact and affect the activation of pathways involved in protein synthesis and degradation.
Using these approaches we showed the existence of a fine alignment between mechanical characteristics of interacting inhomogeneous myocardial elements.
Examining the collective mechanical behaviors of interacting cytoskeletal motors has become increasingly important to dissecting the complex and multifaceted mechanisms that regulate the transport and trafficking of materials in cells.
If this is true then the results illustrate how population level phenomenon, the size-assortative mating, can be directly predicted from a simple mechanical model of interacting individuals.
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